Influence of Deep Breathing on Heart Rate Variability in Parkinson’s Disease: Co-relation with Severity of Disease and Non-Motor Symptom Scale Score
Published: July 1, 2014 | DOI: https://doi.org/10.7860/JCDR/2014/.4550
Mukta Pritam Bidikar, Gayatri J Jagtap, Rahul T Chakor
1. Assistant Professor, Department of Physiology, Topiwala National Medical College & BYL Nair Charitable Hospital, Mumbai, India.
2. Resident, Department of Physiology, Topiwala National Medical College & BYL Nair Charitable Hospital, Mumbai, India.
3. Associate Professor & In-charge Department of Neurology, Topiwala National Medical College & BYL Nair Charitable Hospital, Mumbai, India.
Correspondence
Dr Mukta Pritam Bidikar,
15, Kanchan Mrig, Jeevan Vikas Marg, Koldongi, Andheri East, Mumbai-69, India.
Phone: 9821734441, E-mail: bidikarmukta@gmail.com
Context: Dysautonomia and non-motor symptoms (NMS) in Parkinson’s disease (PD) are frequent, disabling and reduce quality of life of patient.
Aims and Objective: There is a paucity of studies on autonomic dysfunction in PD in Indian population. The study aimed to evaluate autonomic dysfunction in PD patients and co-relate the findings with severity of PD and Non-Motor Symptoms Scale (NMSS) score.
Materials and Methods: We evaluated autonomic function in 30 diagnosed patients of PD (age 55-70 years) and 30 healthy agematched controls by 3 min deep breathing test (DBT). NMSS was used to identify non-motor symptoms and Hoehn and Yahr(HY) Scale to grade severity of PD. The DBT findings were co-related with severity of PD (HY staging) and NMSS score.
Results: DBT was found to be abnormal in 40% while it was on borderline in 33.3% of PD patients. There was a statistically significant difference (p<0.01) between patients and control group for the DBT. NMS were reported across all the stages of PD but with variable frequency and severity for individual symptom. A negative co-relation was found between results of deep breathing test and clinical severity of disease and NMSS score.
Conclusion: Abnormalities of autonomic function and NMS were integral and present across all the stages of PD patients. Early recognition and treatment of these may decrease morbidity and improve quality of life of PD patients.
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